By Robert S. Matson
Microarrays play an more and more major function in drug discovery. the industrial panorama has replaced dramatically during the last few years and researchers have made nice developments in regards to development and use. Now in its moment version, Applying Genomic and Proteomic Microarray know-how in Drug Discovery highlights, describes, and evaluates present medical examine utilizing microarray know-how in genomic and proteomic applications.
Updated and revised to mirror fresh growth within the box, the second one version discusses:
- Expanded omics-driven purposes, together with the parts of metabolomics and chemical biology
- The commercialization of the microarray platform, with a ancient viewpoint aimed toward spotting key technological developments
- Solid-supports (substrates) and floor chemistries at the moment utilized in the production of nucleic acid and protein microarrays
- Different methods to generating microarrays that in attaining spot equality with an identical variety of molecules effectively oriented
- The improvement of the gene expression microarray and consultant applications
- The improvement of protein microarray expertise, together with its historical past and key applications
Unique to this variation is a brand new bankruptcy on multiplex assays that examines the improvement and functions of arrays throughout varied systems. It discusses purposes for qPCR, multiplex lateral move, and multiplex bead assays. It additionally offers platform-to-platform comparisons.
Microarrays stay a useful software for omics-based examine not just in drug discovery, yet within the existence sciences, in scientific examine, and for diagnostic functions all over the world. This quantity offers the present state-of-the-art at the application of this expertise to unravel a bunch of significant organic problems.
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Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition by Robert S. Matson